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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PCLO All Species: 19.39
Human Site: S2053 Identified Species: 60.95
UniProt: Q9Y6V0 Number Species: 7
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y6V0 NP_055325.2 5183 566657 S2053 S L T D S T S S A T L S I P D
Chimpanzee Pan troglodytes XP_001160384 5234 571454 S2060 S L T D S T S S A T L S I P D
Rhesus Macaque Macaca mulatta XP_001094100 3972 424168 L1046 S P S R R Q R L E E A K Q Q R
Dog Lupus familis XP_540507 5080 550145 S2066 S L T D S T S S A T L S I P D
Cat Felis silvestris
Mouse Mus musculus Q9QYX7 5038 547551 S2027 S L T D S T S S A T L S I P D
Rat Rattus norvegicus Q9JKS6 5085 552697 S2069 S L T D S T S S A T L S I P D
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q9PU36 5120 560746 S2041 S A I S D V S S L S S I A L S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001921217 3517 382677 R591 E E I R A Q R R R E R P K T P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.3 27.8 79.5 N.A. 80.6 80.6 N.A. N.A. 61.3 N.A. 37.7 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 98.4 41.1 84.4 N.A. 85.6 85.9 N.A. N.A. 70.9 N.A. 49 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 6.6 100 N.A. 100 100 N.A. N.A. 20 N.A. 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 13.3 100 N.A. 100 100 N.A. N.A. 26.6 N.A. 6.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 13 0 0 13 0 0 0 63 0 13 0 13 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 63 13 0 0 0 0 0 0 0 0 0 63 % D
% Glu: 13 13 0 0 0 0 0 0 13 25 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 25 0 0 0 0 0 0 0 0 13 63 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 13 13 0 0 % K
% Leu: 0 63 0 0 0 0 0 13 13 0 63 0 0 13 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 13 0 0 0 0 0 0 0 0 0 13 0 63 13 % P
% Gln: 0 0 0 0 0 25 0 0 0 0 0 0 13 13 0 % Q
% Arg: 0 0 0 25 13 0 25 13 13 0 13 0 0 0 13 % R
% Ser: 88 0 13 13 63 0 75 75 0 13 13 63 0 0 13 % S
% Thr: 0 0 63 0 0 63 0 0 0 63 0 0 0 13 0 % T
% Val: 0 0 0 0 0 13 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _